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Seasonal influenza triggers significant school closures, especially in southern states, study finds

In a recent study published in The Lancet Regional Health-Americas, researchers examined closures of United States (US) schools due to 11 influenza seasons between 2011 and 2022, determining the frequency and features of these closures. Study:  School closures due to seasonal influenza: a prospective data collection-based study of eleven influenza seasons—United States, 2011–2022…

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New vaccine promises broad protection against SARS-CoV-2 and other sarbecoviruses

Scientists at the Georgia Institute of Technology and the University of Wisconsin, USA, have developed a broad-spectrum vaccine that can protect against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants as well as bat sarbecoviruses. The study is published in the journal Nature Communications. Study: Broad protection against clade 1 sarbecoviruses after…

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Study highlights how age affects nasal cell response to SARS-CoV-2

In a recent study published in the journal Nature Microbiology, researchers investigated age-related differences in nasal epithelial cell (NEC) responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection across pediatric, adult, and older adult groups.  Study: Age-specific nasal epithelial responses to SARS-CoV-2 infection. Image Credit: Designua / Shutterstock Background  Despite effective vaccines, age…

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Research confirms no association between SARS-CoV-2 and childhood asthma diagnoses

A recent study published in Pediatrics investigated whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection influences children's asthma risk. Study:  COVID-19 and Asthma Onset in Children . Image Credit: Pixel-Shot/Shutterstock.com Background Respiratory viral infections in childhood are potential risk factors for asthma. Various studies have reported associations between acute wheezing illnesses in…

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Oregon study finds no clear link between mRNA vaccines and sudden cardiac deaths in young people

In a recent study published in the Morbidity and Mortality Weekly Report (MMWR), a group of researchers investigated the association between messenger Ribonucleic Acid (mRNA) coronavirus disease 2019 (COVID-19) vaccination and sudden cardiac death in Oregon residents aged 16–30 years between June 2021 and December 2022. Study: Assessment of Risk for Sudden…

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Study reveals how SARS-CoV-2 hijacks lung cells to drive COVID-19 severity

In a recent study published in the Journal of Experimental Medicine, researchers identified the cellular tropism and transcriptome consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by infecting human lung tissue and using single-cell ribonucleic acid sequencing (scRNA-seq) to rebuild the transcriptional program in "infection pseudotime" for distinct lung cell types. Lower respiratory infections,…

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Annual COVID-19 vaccine proves to be a wise investment for personal health and pocketbook

In a recent study published in The Journal of Infectious Diseases, a team of researchers from the United States (U.S.) attempted to understand whether individuals experienced any economic benefits in getting an annual coronavirus disease 2019 (COVID-19) vaccine, given that the morbidity and mortality rates associated with the disease have decreased and the government no…

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A balanced take on microbes and disease outcomes

In a recent review published in the journal PNAS, researchers examined the germ theory from a non-centric perspective on infection outcome, considering the variables that influence illness severity while drawing on a known understanding of microbial pathogenesis, evolutionary biology, and pathogen-host interactions. The germ theory revisited: A noncentric view on infection outcome. Image…

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