A 2025 systematic review and meta-analysis published in the Journal of Allergy and Clinical Immunology: In Practice examined polyphenol compounds, including quercetin, in 13 randomized controlled trials involving 823 patients with allergic rhinitis. Seven of those trials focused specifically on seasonal allergies triggered by grass, tree, and ragweed pollen. The review reported that polyphenols significantly reduced total nasal symptom scores, sneezing, and nasal itching compared with placebo. Systematic Review Analyzed 13 Trials Researchers pooled data from 13 randomized controlled trials with 823 participants diagnosed with allergic rhinitis, according to the study published in 2025. Among the seven trials targeting seasonal…
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