A major study of 40,000 brain scans identifies diabetes, frequent alcohol intake and traffic-related air pollution as the three most significant modifiable factors that accelerate the aging of the brain. These factors specifically damage the brain’s most vulnerable network—regions responsible for memory and complex thought that are also the first to deteriorate in Alzheimer’s disease. While genetics play a role, lifestyle choices can influence gene expression, meaning genetic risk is not a fixed destiny for brain health. Beyond the top three, a wide range of modifiable factors—including blood pressure, sleep, social patterns and diet—are interlinked, showing brain aging is a whole-body, whole-life process. The…

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