Meta-Analysis Finds Consistent Brain Choline Deficiency in Anxiety Disorders A new meta-analysis has identified a consistent biological pattern in the brains of individuals with anxiety disorders. The review of 25 brain imaging studies, published in Molecular Psychiatry, found that individuals with anxiety disorders had approximately 8% lower levels of choline-containing compounds in their brains compared to controls. [1] According to the study, the reduction in choline was most pronounced in the prefrontal cortex. This region of the brain is associated with emotional regulation, focus and executive control. The analysis noted that the pattern was observed across generalized anxiety disorder, panic disorder and…
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