An up-close look at how patients respond to the drug at different times and doses adds nuance to a recent finding that Paxlovid does not work for long Covid. An extended course of Paxlovid appears to help some patients with long Covid, according to a case series by UC San Francisco researchers that suggests this…

As 2024 draws to a close, the new year ushers in the opportunity to set new goals for the year ahead. While weight-loss and fitness are staples of New Year resolutions they are commonly known to be the unsustainable resolutions that don't continue past January. 2024 saw a rapid adoption and acceptance of GLP-1s medications…

University of Iowa researchers are recommending all patients be surveyed about their physical activity levels, after a new study underscores the link between physical activity and chronic disease. The study, led by Lucas Carr, associate professor in the Department of Health and Human Physiology, examined responses from more than 7,000 patients at University of Iowa Health…

Improving your brain health in the new year can start with a simple step, talking with your neurologist or primary care physician about 12 factors to protect your brain. The factors are outlined in an Emerging Issues in Neurology article developed by the American Academy of Neurology and published in the December 16, 2024, online…

Everyone knows the health risks of carrying too much fat around the waist and hips, but UVA Health scientists are developing a noninvasive way to assess the health risks of unseen fat around the heart. The researchers, led by Frederick H. Epstein, PhD, of the University of Virginia's Department of Biomedical Engineering, are seeking to…

New study identifies insulin ‘chain-splitting’ during bloodstream transit as a game-changer in understanding and treating diabetes and insulin resistance. Study: Chain splitting of insulin: an underlying mechanism of insulin resistance? Image Credit: Nastasiiaa / Shutterstock In a recent study published in the journal NPJ Metabolic Health and Disease, researchers hypothesize that the…

Discover how cutting-edge spatial aging clocks decode the aging brain, uncovering the dual roles of immune and stem cells in reshaping our understanding of cognitive decline and rejuvenation. Study: Spatial transcriptomic clocks reveal cell proximity effects in brain ageing. Image Credit: VectorMine / Shutterstock In a recent study published in the journal…

Convenient, safe, and non-invasive, "handgrip strength" is a reliable predictor for age-related disease and disability. Now, a groundbreaking study led by the University of South Australia and conducted in collaboration with 140 authors across the globe, has created the world's largest and most geographically comprehensive international norms for handgrip strength, enabling global peer-comparison, health screening…

Using an AI tool, researchers at Karolinska Institutet have analyzed brain images from 70-year-olds and estimated their brains' biological age. They found that factors detrimental to vascular health, such as inflammation and high glucose levels, are associated with an older-looking brain, while healthy lifestyles were linked to brains with a younger appearance. The results are…

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101284, discusses the effect of long-term administration of green tea catechins on aging-related cardiac diastolic dysfunction and decline of troponin I. Aging is an independent risk factor for cardiovascular diseases. Cardiac diastolic dysfunction (CDD), ultimately leading to heart failure with preserved ejection fraction (HFpEF), is prevalent among older…