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Environmental factors and genes play key role in cancer development

Environmental factors and genes play key role in cancer development

A new editorial was published in Oncotarget, Volume 16, on March 10, 2025, titled "EXPOSOMES and GENES: The duo influencing CANCER initiation and progression." In this editorial, Drs. Uzma Saqib, Katherine E. Ricks, Alexander G. Obukhov, and Krishnan Hajela from Devi Ahilya Vishwavidyalaya (DAVV) in Indore, India, discuss how environmental factors, known as exposomes, interact with genes to…

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Gender gaps in peripheral vascular disease impact diagnosis and treatment

Gender gaps in peripheral vascular disease impact diagnosis and treatment

The disparities between men and women in prevalence, risk factors and symptoms of peripheral vascular disease (PVD) have a profound impact on prevention, diagnosis, treatment and outcomes for women, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation. "Peripheral vascular disease is often under-recognized and understudied in women,"…

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Exercise intervention reduces fall risk in elderly women on multiple medications

Exercise intervention reduces fall risk in elderly women on multiple medications

An exercise intervention aimed at elderly women was successful at reducing falls, especially among those with polypharmacy, a new study from the University of Eastern Finland and Kuopio University Hospital shows. The results were published in Scientific Reports. The researchers also found that polypharmacy was associated with poorer results in functional tests measuring physical fitness.…

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Global disparities in Alzheimer’s and dementia burden linked to sociodemographic factors

Global disparities in Alzheimer’s and dementia burden linked to sociodemographic factors

An analysis of the global burden and temporal trends of Alzheimer's disease and other dementias (ADODs) reveals significant cross-country inequalities associated with a series of sociodemographic development-related risk factors, such as education, income, fertility, and health expenditure. The new study in the American Journal of Preventive Medicine, published by Elsevier, calls for the development of…

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Cordycepin helps tired mice run longer and think better, study finds

Cordycepin helps tired mice run longer and think better, study finds

Could a natural fungus compound fight fatigue and sharpen your mind? New research suggests cordycepin might hold the key to boosting endurance and protecting brain function when pushed to the limit. Cordyceps parasitic fungus growing on an ant, also known as zombie-ant fungus, 3D illustration.​​​​​​​ Study: Cordycepin combined with antioxidant effects improves…

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Individualized treatment strategies may be the key to managing pediatric POTS

Individualized treatment strategies may be the key to managing pediatric POTS

Postural orthostatic tachycardia syndrome (POTS) is a form of chronic orthostatic intolerance that primarily affects children and adolescents, leading to debilitating symptoms like lightheadedness, blurred vision, and fatigue upon standing. Unfortunately, the condition is often misunderstood and misdiagnosed, complicating its management. While current treatments range from physical therapies to pharmacological options, their effectiveness can vary…

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Walking more steps and exercise linked to lower risk of death in postmenopausal cancer survivors

Walking more steps and exercise linked to lower risk of death in postmenopausal cancer survivors

Among postmenopausal women with a history of cancer, taking more daily steps and engaging in moderate-to-vigorous physical activity were both associated with a significantly reduced risk of death from cardiovascular disease, according to preliminary research presented at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2025. The meeting will be…

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Asah1 gene plays key role in preventing progression of nonalcoholic fatty liver disease

Asah1 gene plays key role in preventing progression of nonalcoholic fatty liver disease

Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic fatty liver diseases (NAFLD) into more severe forms of liver disease by regulating hepatic lipid homeostasis and cellular maintenance processes. The findings from the new study in The American Journal of Pathology, published by Elsevier, have the…

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