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Study reveals key protein substitutions affect SARS-CoV-2 susceptibility in mammals

Study reveals key protein substitutions affect SARS-CoV-2 susceptibility in mammals

Announcing a new article publication for Zoonoses journal. Zoonotic transmission of severe acute respiratory coronavirus 2 (SARS-CoV-2) has been found to result in infections in more than 30 mammalian species. The SARS-CoV-2 spike protein binds to the host's angiotensin converting enzyme 2 (ACE2) cell surface receptor to gain entry into the cell. ACE2 protein sequence…

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Study projects global antibiotic use to rise by over 50% by 2030

Study projects global antibiotic use to rise by over 50% by 2030

Post-pandemic rebound in antibiotic consumption, especially in middle-income countries, raises concerns about antimicrobial resistance and global health challenges. Study:  Global trends in antibiotic consumption during 2016–2023 and future projections through 2030 . Image Credit: Saiful52/Shutterstock.com In a recent study published in The Proceedings of the National Academy of Sciences, a group…

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SARS-CoV-2 hijacks cholesterol trafficking to fuel infection and evade immune responses

SARS-CoV-2 hijacks cholesterol trafficking to fuel infection and evade immune responses

Researchers uncover how SARS-CoV-2 rewires cholesterol metabolism, highlighting a novel target to combat COVID-19's metabolic and cardiovascular effects. Study: Manipulation of Host Cholesterol by SARS-CoV-2. Image Credit: Kateryna Kon / Shutterstock *Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide…

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