The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for the coronavirus disease 2019 (COVID-19), has been associated with the manifestation of adverse pulmonary conditions, such as pneumonia and acute respiratory distress syndrome (ARDS). A recent Nature Communications study identifies ferroptosis as a major cell death mechanism underlying COVID-19 lung disease. Study:  Fatal COVID-19 pulmonary disease involves ferroptosis.…

In a recent study published in the journal EClinicalMedicine, researchers described the incidence and differences in demographic and clinical characteristics of recorded long coronavirus disease (COVID) in primary care records in England. Study: Clinical coding of long COVID in primary care 2020–2023 in a cohort of 19 million adults: an OpenSAFELY analysis. Image…

Dupilumab is a human monoclonal antibody that blocks the receptor shared by interleukin-4 (IL-4) and IL-13, both of which are key to the development of type 2 inflammation in chronic obstructive pulmonary disease (COPD). A recent study published in The New England Journal of Medicine discusses the results of a second phase III trial on…

Vincent Wasney and his fiancée, Sarah Eberlein, had never visited the ocean. They'd never even been on a plane. But when they bought their first home in Saginaw, Michigan, in 2018, their real estate agent gifted them tickets for a Royal Caribbean cruise. After two years of delays due to the coronavirus pandemic, they set…

A recent study published in The Lancet estimates relative health risks, exposure levels, and burden of disease as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021. Study:  Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global…

In a recent study published in The Lancet Healthy Longevity, researchers conducted an open-label, hybrid effectiveness-implementation, blinded endpoint randomized controlled trial (RCT) to evaluate whether a coach-supported mobile health (mHealth) intervention can reduce dementia risk factors in high-risk, underserved populations. They found that mHealth modestly improved the dementia risk score in the test group compared…

In a recent study published in the journal Humanities and Social Sciences Communications, researchers investigated the role of sentiment and emotional features in detecting fake news by comparing emotions associated with fake and real news. Their findings indicate that integrating emotional features, particularly negative emotions, into machine learning models significantly enhances the accuracy and reliability…

A recent New England Journal of Medicine study assesses whether early blood-pressure control within ambulances leads to favorable clinical outcomes among patients with undifferentiated acute stroke. Study:  Intensive Ambulance-Delivered Blood-Pressure Reduction in Hyperacute Stroke . Image Credit: Jaromir Chalabala / Shutterstock.com Treating stroke Intensive treatment to lower blood pressure levels is often clinically…

Announcing a new article publication for Zoonoses journal. The global coronavirus disease 2019 (COVID-19) pandemic was caused by SARS-CoV-2. This article discussed the development of an mRNA vaccine (LVRNA009) that encoded the S protein of the Wuhan-Hu-1 strain and evaluated the long-term protection potential against SARS-CoV-2 variants. Mice were initially vaccinated with 2 doses of…

In a recent study published in the journal BMC Public Health, researchers determined the frequency of postpartum depression (PPD). They identified associated predictors and coping strategies among mothers in six countries from June to August 2023. Study:  Exploring predictors and prevalence of postpartum depression among mothers: Multinational study . Image Credit: KieferPix /…