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New tARC-seq method enhances precision in tracking SARS-CoV-2 mutations

New tARC-seq method enhances precision in tracking SARS-CoV-2 mutations

In a recent study published in Nature Microbiology, researchers developed a targeted accurate ribonucleic acid (RNA) consensus sequencing (tARC-seq) approach to precisely determine severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutation frequency and types in cell culture and clinical samples. Study:  Targeted accurate RNA consensus sequencing (tARC-seq) reveals mechanisms of replication error affecting…

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Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

In a recent study published in the journal Proceedings of the National Academy of Sciences, a team of researchers from Yale University's School of Medicine and Harvard University used murine models to assess whether intranasally administered neomycin sulfate could evoke antiviral protection against respiratory viruses such as influenza A and severe acute respiratory syndrome coronavirus…

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Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

In a recent study published in the journal BMJ Global Health, researchers compare coronavirus disease 2019 (COVID-19) management guidelines to those published by the World Health Organization (WHO) among different member states. Study:  Comparison of WHO versus national COVID-19 therapeutic guidelines across the world: not exactly a perfect match. Image Credit:…

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New QR4 algorithm outperforms previous models in predicting cardiovascular disease risk

New QR4 algorithm outperforms previous models in predicting cardiovascular disease risk

In a recent study published in Nature Medicine, researchers introduced a new cardiovascular risk prediction algorithm. Study:  Development and validation of a new algorithm for improved cardiovascular risk prediction . Image Credit: Basicdog/Shutterstock.com Background Cardiovascular disease (CVD) remains the leading cause of death worldwide. International guidelines recommend using risk prediction tools targeting at-risk…

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Healthy plant-based diets cut mortality risks for Spain’s seniors

Healthy plant-based diets cut mortality risks for Spain’s seniors

Despite the rising global popularity of healthy pro-vegetarian diets (PVG), including the Mediterranean diet and its derivative DASH (Dietary Approaches to Stop Hypertension), long-term evidence for the benefits of these dietary patterns remains lacking, especially in older populations. In a recent study published in the journal Nutrition, Health, and Aging, researchers investigated the 12-year-long effects…

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Aging affects immune response and virus dynamics in COVID-19 patients, study finds

Aging affects immune response and virus dynamics in COVID-19 patients, study finds

In a recent study published in the journal Science Translational Medicine, researchers investigated the impact of aging on immune response, viral dynamics, and nasal microbiome in 1031 hospitalized coronavirus disease 2019 (COVID-19) patients, using advanced profiling techniques to understand age-related differences in disease severity and immune function. Study: Host-microbe multiomic profiling reveals age-dependent…

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Study shows antipsychotic drugs increase health risks in dementia patients

Study shows antipsychotic drugs increase health risks in dementia patients

In a recent British Medical Journal study, researchers assess the adverse effects associated with the use of antipsychotic drugs in people with dementia. Study:  Multiple adverse outcomes associated with antipsychotic use in people with dementia: population based matched cohort study . Image Credit: Fahroni / Shutterstock.com The role of antipsychotics in dementia management…

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Seasonal influenza triggers significant school closures, especially in southern states, study finds

Seasonal influenza triggers significant school closures, especially in southern states, study finds

In a recent study published in The Lancet Regional Health-Americas, researchers examined closures of United States (US) schools due to 11 influenza seasons between 2011 and 2022, determining the frequency and features of these closures. Study:  School closures due to seasonal influenza: a prospective data collection-based study of eleven influenza seasons—United States, 2011–2022…

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