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New DELIVER guidelines aim to accelerate nanomedicine development

New DELIVER guidelines aim to accelerate nanomedicine development

They're tiny drug-delivery systems 1000 times smaller than a human hair, but while nanomedicines have long been hailed as the future for treating debilitating and life-threatening diseases, their journey from lab to patient has many challenges. Now, new findings from a global team of expert scientists in academia and industry has generated world-first research quality…

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Mucosal COVID-19 vaccine beats mRNA in upper airway defense

Mucosal COVID-19 vaccine beats mRNA in upper airway defense

​​​​​​​ Study:  Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB.1.16 infection in nonhuman primates . Image Credit: TG23/Shutterstock.com In a recent study published in Nature Immunology, a team of researchers from the United States used non-human primate models to compare the protection conferred by an intramuscular booster dose of the bivalent messenger ribonucleic…

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Semaglutide reduced mortality in obese patients by lowering infection-related deaths during COVID-19 pandemic

Semaglutide reduced mortality in obese patients by lowering infection-related deaths during COVID-19 pandemic

Study reveals how semaglutide not only aids in weight loss but also offers a surprising defense against severe infections, including COVID-19, in at-risk populations. Study: The Effect of Semaglutide on Mortality and COVID-19–Related Deaths: An Analysis From the SELECT Trial. Image Credit: MillaF / Shutterstock In a recent study published in The Journal…

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Lifestyle interventions in patients after colorectal cancer treatment

Lifestyle interventions in patients after colorectal cancer treatment

The intervention was feasible for 87% of intervention participants, supporting them in healthy lifestyle changes.  Study: Healthy Eating and Active Lifestyle after Bowel Cancer (HEAL ABC)—feasibility randomised controlled trial. Image Credit: Jo Panuwat D/Shutterstock.com A recent study published in the European Journal of Clinical Nutrition performed a randomized controlled trial (RCT) to…

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COVID-19 treatment reporting in U.S. media lacked scientific rigor, study says

COVID-19 treatment reporting in U.S. media lacked scientific rigor, study says

Study: Descriptions of Scientific Evidence and Uncertainty of Unproven COVID-19 Therapies in US News: Content Analysis Study. Image Credit: Gargantiopa / Shutterstock Despite frequent mentions of scientific evidence, U.S. media largely ignored uncertainties and relied on non-experts, fueling public confusion during the early COVID-19 crisis. In a recent study published in the journal JMIR Infodemiology,…

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Long COVID symptom severity varies widely by age, gender, and socioeconomic status

Long COVID symptom severity varies widely by age, gender, and socioeconomic status

In a recent study published in the journal JRSM Open, researchers analyze self-reported symptoms of long coronavirus disease 2019 (LC) from individuals using a healthcare app to examine the potential impact of demographic factors on the severity of symptoms. The researchers found that LC symptom severity varied significantly by age, gender, race, education, and socioeconomic status.…

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Early viral activity plays critical role in long COVID, study suggests

Early viral activity plays critical role in long COVID, study suggests

In a recent study published in Nature Communications, researchers explored the roles of acute-phase virological dynamics and host immunological responses in post-acute infection sequelae of coronavirus disease 2019 (PASC). Study: Early biological markers of post-acute sequelae of SARS-CoV-2 infection. Image Credit: Starshaker/Shutterstock.com Background Persistent symptoms following acute severe acute respiratory syndrome coronavirus 2…

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