A large-scale study reveals azvudine’s comparable efficacy to Paxlovid, fewer adverse effects, and potential antitumor benefits in patients with liver cancer. Study:  Real‐world effectiveness and safety of oral azvudine versus nirmatrelvir‒ritonavir (Paxlovid) in hospitalized patients with COVID-19: a multicenter, retrospective, cohort study . Image Credit: Cryptographer/Shutterstock.com In a recent study published in…

With cases soaring nearly 2.6 times higher than in previous years, experts warn that climate change and expanding transmission zones are fueling the rise of neuroinvasive Toscana virus infections in Italy. Study: Human neuroinvasive Toscana virus infections in Italy from 2016 to 2023: Increased incidence in 2022 and 2023. Image Credit: Pattarawat…

Study reveals how the JAK inhibitor lowers ACE2 expression and viral entry in individuals with a genetic risk variant linked to autoimmune diseases. Study:  Tofacitinib Mitigates the Increased SARS-CoV-2 Infection Susceptibility Caused by an IBD Risk Variant in the PTPN2 Gene . Image Credit: GB.JSTOCK / Shutterstock.com A recent…

Researchers uncover the alarming overlap between COVID-19, ME/CFS, and severe long COVID symptoms, urging better diagnostics and care strategies. Incidence and Prevalence of Post-COVID-19 Myalgic Encephalomyelitis: A Report from the Observational RECOVER-Adult Study. Image Credit: CKA / Shutterstock A recent study published in the Journal of General Internal Medicine explored the occurrence…

As the nation braces for potential policy shifts under President-elect Donald Trump's "Make America Healthy Again" mantra, the nation's most populous state and largest health care market is preparing for a few changes of its own. With supermajorities in both houses, Democrats in the California Legislature passed — and Democratic Gov. Gavin Newsom signed —…

The U.S. Department of Defense has awarded up to $11.9 million to Oregon State University to invent new drug delivery technologies for protecting members of the military from a range of health threats in combat areas. Once designed, developed and tested, the technologies could also be applied as needed within the general public, said OSU…

Case series suggests longer nirmatrelvir/ritonavir treatments may benefit some individuals with long COVID, highlighting the need for further research into optimal usage. Study:  Impact of extended-course oral nirmatrelvir/ritonavir in established Long COVID: a case series . Image Credit: Ariya J/Shutterstock.com In a recent study published in Communications Medicine, researchers examined the…

Emerging human metapneumovirus (hMPV) strains spark concerns and opportunities in managing respiratory infections in kids. Short Communication: Emerging lineages A2.2.1 and A2.2.2 of human metapneumovirus (hMPV) in pediatric respiratory infections: Insights from India. Image Credit: FOTOGRIN / Shutterstock In a recent study published in the journal IJID Regions, researchers investigated the role…

Case study reveals how human metapneumovirus can cause severe pneumonia even in healthy adults, emphasizing the need for precision diagnostics to tackle under-recognized respiratory threats. Study: The Silent Threat of Human Metapneumovirus: Clinical Challenges and Diagnostic Insights from a Severe Pneumonia Case. Image Credit: Ground Picture / Shutterstock A recent study published…

Study evaluates GPT-4's ability to process medical notes in English, Spanish, and Italian, achieving physician agreement in 79% of cases. Study:  The potential of Generative Pre-trained Transformer 4 (GPT-4) to analyse medical notes in three different languages: a retrospective model-evaluation study . Image Credit: SuPatMaN/Shutterstock.com In a recent study published in…