Exercise, particularly running, can reverse depression-like symptoms caused by an unhealthy diet by restoring key gut metabolites and hormones. A study on rats found that a high-fat, high-sugar diet disrupted gut chemistry and elevated hormones linked to depression, which were normalized by voluntary running. While exercise provided significant mental health benefits, the poor diet blocked the brain’s ability to grow new neurons, showing diet’s critical role in full brain health. The research highlights the gut-brain axis as a key pathway through which physical activity influences mood and metabolism. Experts suggest that consistent, moderate exercise is a powerful tool for mental well-being, even for those…

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