Up to 3 million Americans live with Inflammatory Bowel Disease (IBD) — an umbrella term for conditions including Crohn’s disease and ulcerative colitis. Beyond the daily discomfort, IBD carries a serious hidden risk: people with IBD are significantly more likely to develop colorectal cancer, often at a younger age and with worse outcomes than the general population. While there are some medications that treat IBD, it’s not clear if any of them reduce this risk. Investigators at Weill Cornell Medicine decided to delve into the precise mechanism driving this dramatic increase in colorectal cancer risk — and what they discovered…

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