Indole-3-carbinol (I3C) is a bioactive compound derived from glucobrassicin in cruciferous vegetables. It is formed when crucifers are chopped, chewed or cooked. I3C is said to modulate estrogen metabolism, potentially reducing hormone-related cancers (e.g., breast, prostate). I3C activates pathways like Nrf2 to combat oxidative stress and inflammation. It also supports the activities of liver detox enzymes and helps regulate immune responses. Linked to cancer prevention since the 1970s, studies have confirmed I3C’s role in tumor inhibition and the maintenance of metabolic health. To preserve I3C’s potency, light cooking of cruciferous vegetables is advised. Seek guidance from your health care provider before taking I3C supplements,…
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