New research reveals vitamin B12 deficiency disrupts mitochondrial DNA, impairing muscle energy production and accelerating aging. B12 deficiency allows uracil to infiltrate mitochondrial DNA, causing errors that cripple ATP generation and muscle function. Older adults, vegans, and those with digestive disorders face heightened B12 deficiency risks due to absorption challenges. B12 supplementation in mice doubled muscle energy output, suggesting the potential to reverse age-related mitochondrial decline. Current screening methods may miss early B12 deficiency, as mitochondrial damage occurs before blood tests detect abnormalities. Vitamin B12, long celebrated as the “energy vitamin,” has been quietly orchestrating a critical role in muscle…

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