Research reveals blood sugar’s surprising role in accelerating aging and brain decline – NaturalNews.com

• On Day 8 of the “Regenesis by Jonathan Otto,” aired on Nov. 1, host Jonathan Otto explained that blood sugar is a central regulator of hormones, energy and the rate of aging, with recent science in immunometabolism showing it directly controls immune system function.
• He presented the mechanism by which poor metabolic health threatens the brain, detailing that when blood sugar is dysregulated, the brain’s immune cells cannot effectively clear debris, leading to inflammation and the destruction of brain cells.
• The discussion highlighted that insulin resistance has effects beyond blood sugar, as high insulin levels directly promote fat storage and can disrupt other essential hormones, which is particularly impactful for women approaching perimenopause.
• Otto and his guests emphasized that managing metabolic health is fundamental to disease prevention and longevity, citing research that each increase in insulin resistance accelerates biological aging.
• The experts recommended a practical solution of adopting a diet rich in colorful plants and fiber while minimizing sugar and processed carbohydrates to keep blood sugar under control.

On Day 8 of the “Regenesis by Jonathan Otto,” aired on Nov. 1, host Jonathan Otto explored a body of scientific evidence revealing that blood sugar does far more than just indicate diabetes risk—it may be the key regulator of hormones, energy levels and even the rate at which people age. Recent breakthroughs in immunometabolism show that metabolic health directly controls immune system function, with profound implications for brain health and longevity.

According to neurologist Dr. David Perlmutter, “We are now in a time of embracing something called immunometabolism. The idea that our metabolism, how we create energy from the foods we eat, is involved in regulating our immunity.” This connection explains why people with metabolic issues like diabetes face significantly higher risks for brain degeneration conditions like Alzheimer’s.

The mechanism involves microglial cells, the brain’s immune cells, which depend on proper metabolic function to perform their housekeeping duties. When blood sugar regulation falters, these cells can’t effectively clear brain debris, leading to inflammation and destruction of brain cells. “When we’re metabolically compromised, as are probably 93 percent of Americans in one way or another, it threatens the metabolism of our brain’s immune cells,” Perlmutter explained.

Functional medicine expert Dr. Daniel Nuzum adds that insulin resistance affects more than just blood sugar. “If you have high insulin, you will also have high fat storage capacity. Your ability to put on mass is dependent on the amount of insulin in your bloodstream.” This hormonal disruption can particularly impact women approaching perimenopause, as excess insulin crowds out space for other essential hormones.

According to BrightU.AI’s Enoch, “perimenopause is the transitional phase leading up to menopause, characterized by hormonal fluctuations that cause symptoms like irregular periods and hot flashes. It signifies the natural progression into the end of a woman’s reproductive years.”

The solution lies in comprehensive metabolic health management. Experts recommend monitoring blood sugar levels, possibly with continuous glucose monitors and adopting a diet rich in colorful plants and fiber while minimizing sugar and processed carbohydrates. As Perlmutter advised, “Choosing a diet that keeps your blood sugar under control is really one of the most important fundamentals.”

Recent research confirms the urgency: A National Health and Nutrition Examination Survey found that each increase in insulin resistance accelerates biological aging by 1.64 years, making metabolic health management crucial for both disease prevention and longevity.

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Sources include:

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