The U.S. Food and Drug Administration (FDA) maintains a list of substances “Generally Recognized as Safe” (GRAS) for use in food. While these substances are considered safe under the conditions of their intended use, some have raised concerns among researchers, health advocates, and consumers due to potential health risks.

The GRAS (Generally Recognized as Safe) loophole, established in 1958, was initially intended to exempt common, harmless substances like salt and vinegar from rigorous safety testing. However, it has since become a significant regulatory gap, allowing companies to self-certify chemicals as safe without FDA oversight or scientific evidence. This self-regulation has led to widespread use of untested or potentially harmful additives in the U.S. food supply. For instance, titanium dioxide, a whitening agent linked to chromosomal damage, is banned in the European Union but remains in over 1,900 U.S. products. Similarly, potassium bromate, a dough conditioner banned in multiple countries due to cancer risks, is still used in over 200 U.S. products.

New HHS Secretary Robert F. Kennedy Jr. argues that the GRAS system prioritizes corporate convenience over public health, leaving consumers exposed to potentially dangerous chemicals. He announced this week that HHS now seeks to end the FDA’s GRAS rule.

Below is a list of 43 FDA-approved GRAS food additives and chemicals that have been the subject of concern regarding human health. Note that the safety of these substances is often debated, and regulatory agencies continue to monitor their use, but due to their ubiquitous nature in the American food supply, health concerns are legitimate in most circumstances.

FDA to take closer look at GRAS food additives and chemicals

1. Aspartame – Artificial sweetener linked to potential neurological effects.

2. High-Fructose Corn Syrup (HFCS) – Associated with obesity and metabolic disorders.

3. Sodium Nitrite/Nitrate – Preservative in processed meats; linked to cancer risk.

4. Butylated Hydroxyanisole (BHA) – Antioxidant preservative; potential carcinogen.

5. Butylated Hydroxytoluene (BHT) – Antioxidant preservative; potential carcinogen.

6. Monosodium Glutamate (MSG) – Flavor enhancer; linked to neurological effects in sensitive individuals.

7. Artificial Food Dyes (e.g., Red 40, Yellow 5, Blue 1) – Linked to hyperactivity in children and potential carcinogenicity.

8. Potassium Bromate – Flour additive; potential carcinogen.

9. Propyl Gallate – Preservative; potential endocrine disruptor.

10. Tertiary Butylhydroquinone (TBHQ) – Preservative; potential carcinogen.

11. Sodium Benzoate – Preservative; linked to hyperactivity and potential carcinogenicity.

12. Potassium Sorbate – Preservative; potential allergen and irritant.

13. Sulfites – Preservatives; linked to allergic reactions and asthma.

14. Carrageenan – Thickening agent; linked to gastrointestinal inflammation.

15. Polysorbate 80 – Emulsifier; linked to gut microbiome disruption.

16. Soy Lecithin – Emulsifier; potential allergen and GMO concerns.

17. Xanthan Gum – Thickening agent; potential digestive issues.

18. Artificial Sweeteners (e.g., Sucralose, Saccharin) – Linked to metabolic and gut health issues.

19. Trans Fats (Partially Hydrogenated Oils) – Linked to heart disease (now largely banned but still in some products).

20. Azodicarbonamide – Flour bleaching agent; potential respiratory and carcinogenic risks.

21. Calcium Propionate – Preservative; linked to behavioral issues in children.

22. Sodium Aluminum Phosphate – Leavening agent; potential neurotoxin.

23. Calcium Disodium EDTA – Preservative; potential kidney and liver toxicity.

24. Brominated Vegetable Oil (BVO) – Emulsifier; linked to neurological and organ toxicity.

25. Diacetyl – Flavoring agent; linked to respiratory issues.

26. Propylene Glycol – Humectant; potential allergen and irritant.

27. Titanium Dioxide – Food coloring; potential carcinogen.

28. Sodium Saccharin – Artificial sweetener; potential carcinogen.

29. Acesulfame Potassium (Ace-K) – Artificial sweetener; potential carcinogen.

30. Sodium Stearoyl Lactylate – Emulsifier; potential allergen.

31. Sodium Metabisulfite – Preservative; linked to allergic reactions.

32. Sodium Erythorbate – Preservative; potential carcinogen.

33. Calcium Sulfate – Firming agent; potential allergen.

34. Sodium Caseinate – Milk derivative; potential allergen.

35. Hydrolyzed Vegetable Protein (HVP) – Flavor enhancer; potential allergen.

36. Autolyzed Yeast Extract – Flavor enhancer; contains MSG.

37. Maltodextrin – Thickening agent; potential glycemic impact.

38. Sodium Hexametaphosphate – Preservative; potential kidney toxicity.

39. Sodium Tripolyphosphate – Preservative; potential kidney toxicity.

40. Calcium Chloride – Firming agent; potential irritant.

41. Ammonium Chloride – Dough conditioner; potential irritant.

42. Sodium Aluminum Sulfate – Leavening agent; potential neurotoxin.

43. Sodium Phosphate – Preservative; linked to kidney and heart issues.

Important Notes:

• The safety of these substances is often context-dependent, including the dose, frequency of consumption, and individual sensitivity.

• Many of these additives are considered safe in small amounts but may pose risks with excessive or long-term exposure.

• Consumers concerned about these additives should read food labels and opt for minimally processed foods when possible.

• Robert F. Kennedy Jr. is directing the FDA to take a closer look at these food additives and chemicals and is working with the food industry to improve the American food supply.

Sources include:

TheEpochTimes.com

FDA.gov

Enoch, Brighteon.ai