The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell.  It's a core function, but little studied in the setting of cancer immunology, especially when compared to other organelles like the mitochondria or endoplasmic reticulum.  "So we were interested in looking a…

Researchers at University of Tsukuba analyzed data from middle-aged workers who had received Specific Health Guidance—a revolutionary system implemented by the Japanese Ministry of Health, Labor, and Welfare to improve lifestyle habits for individuals with metabolic syndrome and those at presumptive risk of metabolic syndrome. Using machine learning approaches, they explored the factors that affect…

Three research institutions in Barcelona have teamed up to launch the world's first Joint Program on Evolutionary Medical Genomics. The initiative, launched this week at an inaugural symposium in Barcelona Biomedical Research Park (PRBB), is a collaboration between the Centre for Genomic Regulation (CRG), the Department of Medicine and Life Sciences at the Universitat Pompeu…

A new simulator gives nursing students hands-on practice with vital procedures like mechanical ventilation and tracheal suctioning in children. Researchers at Hokkaido University in Japan have created a new training tool to equip nursing students with the skills needed in caring for children who require mechanical ventilation and tracheal suctioning. In a study published in…

A Finnish study found that prolonged standing at work had a negative impact on the research participants' 24-hour blood pressure. In contrast, spending more time sitting at work was associated with better blood pressure. The study suggests that activity behaviour during working hours may be more relevant to 24-hour blood pressure than recreational physical activity.…

 In a new study published in the European Heart Journal, researchers at Karolinska Institutet show that genetic traits influence the cellular composition of atherosclerotic plaques, which over time will affect the risk of such lesions to cause a stroke or heart attack. The new knowledge can be used to improve the risk assessment and treatment…

As rates of obesity, as defined by body mass index (BMI), continue to climb in the United States, so have efforts to lose weight, including a new era of weight-loss drugs. Yet a new systematic review and meta-analysis published today in the British Journal of Sports Medicine found that cardiorespiratory fitness was a stronger predictor…

Most cases of cardiac arrest during sport are likely to be preventable. In addition, the emergency response with cardiopulmonary resuscitation (CPR) and defibrillators within the sports context can be improved. This has been shown in a thesis from the University of Gothenburg. Swedish ambulance services report around 6,000 cases of sudden cardiac arrest annually. These…

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns. Fortunately, this attention to cholesterol has prompted the development of cholesterol-lowering drugs called statins and lifestyle interventions like dietary and exercise regimens. But what if there's more…

Popular anti-obesity drugs continue to show cardiovascular benefits beyond weight loss, according to several new papers published in JACC, the flagship journal of the American College of Cardiology, that are being simultaneously presented at the American Heart Association's 2024 Scientific Sessions. JACC is publishing two secondary analyses on the impact of GLP-1 medications in improving…