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Study projects global antibiotic use to rise by over 50% by 2030

Study projects global antibiotic use to rise by over 50% by 2030

Post-pandemic rebound in antibiotic consumption, especially in middle-income countries, raises concerns about antimicrobial resistance and global health challenges. Study:  Global trends in antibiotic consumption during 2016–2023 and future projections through 2030 . Image Credit: Saiful52/Shutterstock.com In a recent study published in The Proceedings of the National Academy of Sciences, a group…

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SARS-CoV-2 hijacks cholesterol trafficking to fuel infection and evade immune responses

SARS-CoV-2 hijacks cholesterol trafficking to fuel infection and evade immune responses

Researchers uncover how SARS-CoV-2 rewires cholesterol metabolism, highlighting a novel target to combat COVID-19's metabolic and cardiovascular effects. Study: Manipulation of Host Cholesterol by SARS-CoV-2. Image Credit: Kateryna Kon / Shutterstock *Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide…

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Phase 2 study evaluates safety and efficacy of asunercept in COVID-19 patients

Phase 2 study evaluates safety and efficacy of asunercept in COVID-19 patients

While the trial confirmed asunercept’s safety and tolerability, it failed to achieve statistically significant improvement in clinical outcomes compared to standard care. Study:  Efficacy and safety of asunercept, a CD95L-selective inhibitor, in hospitalised patients with moderate-to-severe COVID-19: ASUNCTIS, a multicentre, randomised, open-label, controlled, phase 2 trial . Image Credit: Pormezz/Shutterstock.com In…

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Genomic surveillance could revolutionize the fight against antimicrobial resistance

Genomic surveillance could revolutionize the fight against antimicrobial resistance

During the COVID-19 pandemic, genomic surveillance proved vital in helping understand the evolution and spread of the SARS-CoV-2 virus. Now, an international group of researchers is calling for its potential to be harnessed to tackle antimicrobial resistance (AMR), a major global challenge that could ultimately result in many more deaths than the coronavirus pandemic. AMR…

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Cognitive behavioral therapy shows promise for prolonged grief disorder

Cognitive behavioral therapy shows promise for prolonged grief disorder

A clinical trial finds that integrative cognitive behavioral therapy (PG-CBT) is more effective than present-centered therapy (PCT) in reducing grief severity and comorbid symptoms after treatment, providing hope for individuals with prolonged grief disorder. Study:  Grief-Specific Cognitive Behavioral Therapy vs Present-Centered Therapy . Image Credit: Microgen/Shutterstock.com In a recent study published…

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Futuristic AI-powered virtual lab designs potent SARS-CoV-2 nanobodies

Futuristic AI-powered virtual lab designs potent SARS-CoV-2 nanobodies

Harnessing AI agents and human expertise, researchers accelerate the design of innovative nanobodies to combat evolving SARS-CoV-2 variants. Study: The Virtual Lab: AI Agents Design New SARS-CoV-2 Nanobodies with Experimental Validation. Image Credit: Shutterstock AI *Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should…

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